Calcium: Amplitude, Duration, or Location?

Crossed cerebellar diaschisis: related to lesion location or disease duration?

TO THE EDITOR: The article by Kim et al. (/) draws the conclusion that the location, rather than the extent and severity, of the lesion may be the major determinant for the occurrence and magnitude of crossed cerebellar diaschisis (CCD) in patients with cerebral infarction. They reported that both the frequency and severity of CCD are greater in patients with infarction in either the frontopari...

Calcium Input Frequency, Duration and Amplitude Differentially Modulate the Relative Activation of Calcineurin and CaMKII

NMDA receptor dependent long-term potentiation (LTP) and long-term depression (LTD) are two prominent forms of synaptic plasticity, both of which are triggered by post-synaptic calcium elevation. To understand how calcium selectively stimulates two opposing processes, we developed a detailed computational model and performed simulations with different calcium input frequencies, amplitudes, and ...

Defibrillation Shock Amplitude, Location and Timing

Meeting profiles: size, duration, and location

Managers spend a majority of their days in face-to-face meetings so it is not surprising that meeting support is becoming an important focus of information technology. But meetings vary wideIy in size, duration, and location. Some are briqf deskside meetings between two or three people, others are lengthy conference room meetings with a dozen or more participants. Thus, support needs may also v...

Sensitivity of smoothness measures to movement duration, amplitude, and arrests.

Studies of sensory-motor performance, including those concerned with changes because of age, disease, or therapeutic intervention, often use measures based on jerk, the time derivative of acceleration, to quantify smoothness and coordination. However, results have been mixed: some researchers report sensitive discrimination of subtle differences, whereas others fail to find significant differen...